When I strat SimPE, the pjse tables seem to be throwing exceptions left and right.  The error report for that is:

Message:
The type initializer for 'pjse.FileTable' threw an exception.

SimPE Version:
Default (0.72.1.33855).

Exception Stack:
System.TypeInitializationException: The type initializer for 'pjse.FileTable' threw an exception. ---> System.IO.IOException: The process cannot access the file 'C:\Users\Sara\Documents\EA Games\The Sims 2\Downloads\_EnableColorOptionsGMND.package' because it is being used by another process.
  at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
  at System.IO.FileStream.Init(String path, FileMode mode, FileAccess access, Int32 rights, Boolean useRights, FileShare share, Int32 bufferSize, FileOptions options, SECURITY_ATTRIBUTES secAttrs, String msgPath, Boolean bFromProxy)
  at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access)
  at SimPe.Packages.StreamFactory.UseStream(String filename, FileAccess fa, Boolean create)
  at SimPe.Packages.File.ReloadFromFile(String filename)
  at SimPe.Packages.PackageMaintainer.LoadPackageFromFile(String filename, Boolean sync)
  at SimPe.Packages.File.LoadFromFile(String flname)
  at pjse.FileTable.Add(String v, Boolean recurse, Boolean isMaxis, Boolean isFixed)
  at pjse.FileTable.Refresh(Boolean loadEverything)
  at pjse.FileTable.Refresh()
  at pjse.FileTable..cctor()
  --- End of inner exception stack trace ---
  at pjse.FileTableTool.IsEnabled(IPackedFileDescriptor pfd, IPackageFile package)
System.IO.IOException: The process cannot access the file 'C:\Users\Sara\Documents\EA Games\The Sims 2\Downloads\_EnableColorOptionsGMND.package' because it is being used by another process.
  at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
  at System.IO.FileStream.Init(String path, FileMode mode, FileAccess access, Int32 rights, Boolean useRights, FileShare share, Int32 bufferSize, FileOptions options, SECURITY_ATTRIBUTES secAttrs, String msgPath, Boolean bFromProxy)
  at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access)
  at SimPe.Packages.StreamFactory.UseStream(String filename, FileAccess fa, Boolean create)
  at SimPe.Packages.File.ReloadFromFile(String filename)
  at SimPe.Packages.PackageMaintainer.LoadPackageFromFile(String filename, Boolean sync)
  at SimPe.Packages.File.LoadFromFile(String flname)
  at pjse.FileTable.Add(String v, Boolean recurse, Boolean isMaxis, Boolean isFixed)
  at pjse.FileTable.Refresh(Boolean loadEverything)
  at pjse.FileTable.Refresh()
  at pjse.FileTable..cctor()

Source:
pjse.filetable.plugin

Execution Stack:
at pjse.FileTableTool.IsEnabled(IPackedFileDescriptor pfd, IPackageFile package)

Windows Version:
Vista

.NET Version:
2.0.50727.3603

My game isn't running, either, just BodyShop.  (I saw that as a possible cause in another thread) and when I try to import a mesh, I get another error:

Message:
Unable to Start ToolPlugin.

SimPE Version:
Default (0.72.1.33855).

Exception Stack:
System.IO.IOException: The process cannot access the file 'C:\Program Files (x86)\EA GAMES\The Sims 2 Apartment Life\TSData\Res\3D\Sims03.package' because it is being used by another process.
  at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
  at System.IO.FileStream.Init(String path, FileMode mode, FileAccess access, Int32 rights, Boolean useRights, FileShare share, Int32 bufferSize, FileOptions options, SECURITY_ATTRIBUTES secAttrs, String msgPath, Boolean bFromProxy)
  at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access)
  at SimPe.Packages.StreamFactory.UseStream(String filename, FileAccess fa, Boolean create)
  at SimPe.Packages.File.ReloadFromFile(String filename)
  at SimPe.Packages.PackageMaintainer.LoadPackageFromFile(String filename, Boolean sync)
  at SimPe.Packages.File.LoadFromFile(String flname)
  at pj.BodyMeshExtractor.addFromPkg(String name, UInt32 type, String pkg)
  at pj.BodyMeshExtractor.findAndAdd(String name, UInt32 type, String source)
  at pj.BodyMeshExtractor.Main()
  at pj.BodyMeshExtractor.ShowDialog(IPackedFileDescriptor& pfd, IPackageFile& package)
  at SimPe.ToolMenuItemExt.ClickItem(Object sender, EventArgs e)

Source:
mscorlib

Execution Stack:
at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
  at System.IO.FileStream.Init(String path, FileMode mode, FileAccess access, Int32 rights, Boolean useRights, FileShare share, Int32 bufferSize, FileOptions options, SECURITY_ATTRIBUTES secAttrs, String msgPath, Boolean bFromProxy)
  at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access)
  at SimPe.Packages.StreamFactory.UseStream(String filename, FileAccess fa, Boolean create)
  at SimPe.Packages.File.ReloadFromFile(String filename)
  at SimPe.Packages.PackageMaintainer.LoadPackageFromFile(String filename, Boolean sync)
  at SimPe.Packages.File.LoadFromFile(String flname)
  at pj.BodyMeshExtractor.addFromPkg(String name, UInt32 type, String pkg)
  at pj.BodyMeshExtractor.findAndAdd(String name, UInt32 type, String source)
  at pj.BodyMeshExtractor.Main()
  at pj.BodyMeshExtractor.ShowDialog(IPackedFileDescriptor& pfd, IPackageFile& package)
  at SimPe.ToolMenuItemExt.ClickItem(Object sender, EventArgs e)

Windows Version:
Vista

.NET Version:
2.0.50727.3603

So then I read in another thread to try the QA version of SimPE.  I also still have the other SimPE installed as well.   This time the start-up error and the tool still won't load, either.

Message:
The process cannot access the file 'C:\Users\Sara\Documents\EA Games\The Sims 2\Downloads\_EnableColorOptionsGMND.package' because it is being used by another process.

SimPE Version:
Default (0.73.44.37511).

Exception Stack:
System.IO.IOException: The process cannot access the file 'C:\Users\Sara\Documents\EA Games\The Sims 2\Downloads\_EnableColorOptionsGMND.package' because it is being used by another process.
  at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
  at System.IO.FileStream.Init(String path, FileMode mode, FileAccess access, Int32 rights, Boolean useRights, FileShare share, Int32 bufferSize, FileOptions options, SECURITY_ATTRIBUTES secAttrs, String msgPath, Boolean bFromProxy)
  at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access)
  at SimPe.Packages.StreamFactory.UseStream(String filename, FileAccess fa, Boolean create)
  at SimPe.Packages.File.ReloadFromFile(String filename)
  at SimPe.Packages.PackageMaintainer.LoadPackageFromFile(String filename, Boolean sync)
  at SimPe.Packages.File.LoadFromFile(String flname)
  at pjse.FileTable.Add(String v, Boolean recurse, Expansions ep, Boolean isFixed)
  at pjse.FileTable.Refresh(Boolean loadEverything)
  at pjse.FileTable.get_GFT()
  at pjse.FileTableTool.IsEnabled(IPackedFileDescriptor pfd, IPackageFile package)

Source:
mscorlib

Execution Stack:
at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
  at System.IO.FileStream.Init(String path, FileMode mode, FileAccess access, Int32 rights, Boolean useRights, FileShare share, Int32 bufferSize, FileOptions options, SECURITY_ATTRIBUTES secAttrs, String msgPath, Boolean bFromProxy)
  at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access)
  at SimPe.Packages.StreamFactory.UseStream(String filename, FileAccess fa, Boolean create)
  at SimPe.Packages.File.ReloadFromFile(String filename)
  at SimPe.Packages.PackageMaintainer.LoadPackageFromFile(String filename, Boolean sync)
  at SimPe.Packages.File.LoadFromFile(String flname)
  at pjse.FileTable.Add(String v, Boolean recurse, Expansions ep, Boolean isFixed)
  at pjse.FileTable.Refresh(Boolean loadEverything)
  at pjse.FileTable.get_GFT()
  at pjse.FileTableTool.IsEnabled(IPackedFileDescriptor pfd, IPackageFile package)

Windows Version:
Vista

.NET Version:
2.0.50727.3603 

I didn't have errors with the older versions, I just upgraded today and now the program seems to be freaking out.  Is it because I have a 64-bit system?  It's days like this I miss xp...